In the past, the most common test for diagnosing infectious mononucleosis was the heterophile antibody test, which involves testing heterophile antibodies by agglutination of guinea pig, sheep and horse red blood cells. The signs of mono include fever, fatigue, sore throat, and swollen lymph nodes.
Only half the patients presenting with the symptoms held by mononucleosis and a positive heterophile antibody test (monospot test) meet the entire criteria. One key procedure is to differentiate between infectious mononucleosis and mononucleosis-like symptoms.
If mono is accompanied by a streptococcal infection of the throat, an antibiotic will be prescribed to treat that condition. In severe cases, corticosteroid drugs that reduce swelling may be prescribed.
With an enlarged spleen: avoid contact sports for at least four weeks.
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